Yes, he had three.
A daughter, Caroline Kennedy, born November 27, 1957. She expressed an interested in being appointed to Clinton's vacant Senate seat from New York. (After Senator Hilary Clinton was appointed as the current Secretary of State, her Senate seat was vacant.)
A son, John F. Kennedy, Jr. born November 25, 1960, and died in a self piloted airplane crash on July 16, 1999; killing himself, his wife and his wife's sister (his sister-in law).
A son, Patrick Bouvier Kennedy, born August 7, 1963, died August 9, 1963. He was born 5 1/2 weeks early, by emergency Cesarean delivery. He was just 4 pounds 10 1/2 ounces, and ultimately died of RDS or Respiratory Distress Syndrome.
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John F. Kennedy's wife was Jacquenline Kennedy Onassis. His children were Caroline Kennedy , John F. Kennedy Jr. , Patrick Bouvier and Arabella Kennedy.
Joseph Kennedy was the father of John F. Kennedy. It has been postulated that Joseph Kennedy smuggled alcohol into the United States during Prohibition.
bootleggers were people who illegally sold alcohol.
John F. Kennedy, Jr.
President Reagan appointed Justice Anthony Kennedy to succeed Justice Lewis F. Powell, Jr., in 1988 following Justice Powell's retirement.