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Yes. She had a half brother named Henry IV and a whole brother named Alfonso. Henry IV was her older brother. Queen Isabella was born in Madrigal de las Torres, Spain on April 22, 1451 and had died in Medina del Campo, Spain on November 26, 1504. If yu dont believe meh then go to thins website...... www.nndb.com/people/221/000092942/ ok there yu go!

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Q: Did Queen Isabella of Spain have any siblings?
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