Interstate commerce is business that takes place in two or more states, like crossing from New Jersey into New York, or making something in one state but selling it in another state (or states.) Intrastate commerce means that only one state is involved. This is simpler in terms of regulations (California has different car emission standards than some other states) and taxation.
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President Grover Cleveland signed the Interstate Commerce Act of 1887 and created the Interstate Commerce Commission (ICC), the U.S. government's first regulatory agency
Interstate commerce commission
When state regulation negatively affect interstate commerce, commerce must yield to the regulations.
The regulatory body in the US is the Interstate Commerce Commission.
The Interstate Commerce Commission was not directly related to political corruption.