No US President has had a last name that ended in X; however, in 1920 James Cox ran as the Democratic candidate against Warren Harding. Harding's victory in that election remains the largest percentage margin of victory ever.
The presidents were
* d Grover Cleveland * d Grover Cleveland * d Gerald Ford * d James A. Garfield * e Calvin Coolidge * e Millard Fillmore * e James Monroe * e Franklin Pierce * g Warren G. Harding * h George Bush * h George W. Bush * k James K. Polk * n James Buchanan * n Bill Clinton * n William Henry Harrison * n Benjamin Harrison * n Thomas Jefferson * n Andrew Jackson * n Andrew Johnson * n Lyndon B. Johnson * n Abraham Lincoln * n James Madison * n Richard Nixon * n Ronald Reagan * n Harry S Truman * n Martin Van Buren * n George Washington * n Woodrow Wilson * r Chester A. Arthur * r Jimmy Carter * r Dwight D. Eisenhower * r Herbert Hoover * r John Tyler * r Zachary Taylor * s John Adams * s John Quincy Adams * s Rutherford B. Hayes * t Ulysses S. Grant * t Theodore Roosevelt * t Franklin D. Roosevelt * t William Howard Taft * y John F. Kennedy * y William McKinley
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There have been no U.S. Presidents whose last name started with S.
John Quincy Adams
Ronald Reagan Calvin Coolidge Woodrow Wilson Herbert Hoover
Jefferson City,MOLincoln,NEMadison,WIJackson,MS
Both were Vice Presidents who became president after an assassination:Andrew Johnson (17th President), who succeeded Abraham LincolnLyndon Johnson (36th President), who succeeded John F. Kennedy.