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There were actually four presidents to die in office during the 20th Century, though only two died of natural causes.

William McKinley starts us off on September 14, 1901- Assassinated

Warren G. Harding- August 2, 1923- Either heart attack or stroke

Franklin D. Roosevelt- April 12, 1945- Cerebral Hemorrhage

John F. Kennedy- November 22, 1963- Assassinated

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16y ago
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16y ago

William Henry Harrison died within one month after inauguration. Garfield died within 8 months of inauguration.

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13y ago

No US presidents died in 1999 but you posed your question in US presidents category,

so I wonder what you are thinking of.

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Q: Which two presidents died in office in the 20th century?
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