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This is, of course, a question concerning opinion. In European history, some would argue that Catherine de Medici was the bad guy of the 16th century. She basically launched the St. Bartholomew's Day Massacre, which killed thousands of Huguenots (French Protestants).
the brides in the 16th century were expected to follow their husbands in all decisions
William and Mary? They were good people. I don't know...
no, the 16th century begins with the year 1500 and ends with the year 1599. the year 1600 begins the 17th century.
the 16th century.