Burr believed that Hamilton was the sole detriment to the rise of his political career, namely. Hamilton had intervened, for Jefferson, in the nasty election of 1800, and had also intervened in the race for the governor of New York later. Both times, Hamilton had ruined Burr's chances. This animosity led Burr to kill Hamilton in 1804.
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Hamilton and Burr were political rivals. Hamilton, a Federalist, used his political influence to convince The House to break the tie breaker for President by picking Jefferson over Burr, a Republican.
The Burr-Hamilton duel occurred on July 11, 1804. Hamilton died July 12.
Alexander Hamilton opposed Burr and won the election in 1804.
Aaron Burr
No one knows specifically what Hamilton said. He and another man apparently remarked to a Dr. Cooper that they considered Burr too dangerous to run the government. Dr. Cooper stated that he could quote "still more despicable" statements Hamilton had made about Burr, but didn't.
Although Hamilton disliked Jefferson he thought Jeffersons veiws, were better for the country