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There could of been many things that had an impact on the ancient world. Greece has a major impact in the ancient times from their math and science styles.
How did the river systems impact the ancient worldRead more: How_did_the_fiver_systems_impact_the_ancient_world
They did create astronomy which is kinda of a scientific contribution and an impact on the ecosystem.
Who knows? if you have not found the answer yet, you probably won't be finding it here. sorry
Cleopatra's impact on Egypt was negative. She raised the taxes in order to pay off her father's debt. She allowed the country's infrastructure to crumble and she eventually lost the entire country to Rome.