There have been people born so severely deformed as to have only one eye. Such may be the source of the legend of the cyclops, although such cannot be confirmed.
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Polyphemus
first off cyclops arent real in my opion but from what ive read in books is that they will tie them up from the ceiling and let them die when there dead he uses the flesh as food by putting it in a fire if you belive cyclops are real that might happen
In the Odyssey... Polythemus as well as the other Cyclops ate sheep, but Polytheus actually ate a few of Odysseus' crew members.
Odysseus taunts the cyclops as he sails away, giving Polyphemus his real name.
To trick the cyclopes into telling the others that "nobody" has tricked him.