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She hung herself.
Cleopatra was under guard in her beautiful Mausoleum in Alexandria when she killed herself.
Octavian did not kill Cleopatra. Cleopatra killed herself. She committed suicide.
She did not kill herself! Epimetheus married Pandora. They had a daughter, Pyrrha, who married Deucalion and survived the deluge with him. This deluge killed everybody else on Earth (including Pandora, of course).
Cleopatra killed herself in August of 30 BC.