With support of Andrew Jackson, congress did the Indian removal act of all Indians east of the Mississippi river. They were moved to Indian territory which is now modern day Oklahoma.
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The War of 1812 secured existing US boundaries and defeated tribes in the Ohio and Mississippi valleys. This along with the Indian Removal Act of 1830, opened the door to significant westward expansion by people across America .
Gadsden Purchase
They were looking for a water route across to the ocean and the continent.
If you mean the U.S as in North America then....A Native American Indian namd Ochowatstaki Lureyitthim
During the 1800's, an abolitionist was considered someone who was for the immediate removal of slavery across the entire U.S. and was willing to resort to any means to get it, including violence.