In July & August of 1931 around 3 million people died from a flood in China. That was over a period of weeks, rather than a single day.
January 23, 1556, 830 thousand people died in an earthquake in China. That would probably represent the single bloodiest day in human history.
The firestorm created in Tokyo, Japan March 9, 1945 claimed about 97,000 lives.
For a more protracted period of time, 8:15 (local time) Monday morning, August 6th, 1945, somewhere from 120 to 140 thousand Japanese were killed by the first nuclear weapon used in war.
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The bloodiest single day battle was the battle of Antietam which occured on September 1862.
Battle of the Sea of Japan; also known as the Battle of Tsushima. History's only decisive battleship fleet action.
The Great Depression
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The significance of Roanoke VA in American History is small compared to other history times, though there is a small part of history in the city. The supposed group of people who lived in the colony in 1885 to 1887 had all up and left for some reason or just disappeared. This is known now as "The Lost Colony".
John Pope was a career United States Army officer and Union general in the American Civil War. He is best known for his defeat at the Second Battle of Bull Run in the East.