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No. It replaced it with a deal - California to be admitted as a free state, with certain concessions to appease the South, including tightening-up the Fugitive Slave Act. It was the last-minute Crittenden Compromise that was meant to restore the Missouri Line, but Lincoln rejected this compromise, because it would have allowed some extension of slavery.
because something broke it
Because of slavery
The Dred Scott Case completely nullified the Missouri Compromise. It ruled that slavery was protected under the 5th Amendment because slaves were property. The verdict was that slavery could not be outlawed in any territory.
Increasing influence of the Abolitionists in Congress, and hostility towards the new territories that were entitled to practise slavery because they were on the right side of the Missouri parallel.