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The opinion is pretty much split down the middle and hinges on whether or not there was intent. First of all this number is controversial and varies amongst historians and critics. The numbers of deaths are also estimated from a time span of centuries with deaths attributed to a variety of causes. Many of the deaths can be attributed to disease which would be classified as death by natural causes. However, European Americans soon became aware of the lack of immunity to common diseases the natives had. There have been accusations that blankets that had been infected with smallpox were deliberately given to Native Americans. If you add to that the brutality of the Indian Wars, disease and famine as well as lives lost on the "Trial of Tears", many causes can be attributed to the deaths.

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Q: Historians agree that the Native American population of about 145 million in the Americas was systematically and intentionally destroyed by Europeans?
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