Horses. -Apex
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Europeans
Yes.
Well there is the slasve trade and christopher columbus finding the Americas which resulted in the columbian exchange and the inclussion of the americas in global trade aside from the europeans who fought for the supremacy of the americas and the spread of disease.
the Columbian exchange was a dramatically widespread exchange of animals, foods, human populations including the slaves too.
The Columbian Exchange is named such because it all started when Columbus mistakenly landed in the Caribbean in 1492 (also the year the Columbian exchange is noted for starting). It is also referred to as triangular trade (sugar/agriculture from Americas to Europe, manufactured goods from Europe to Africa, and slaves from Africa to the Americas).