When the people of the United States heard about the Ostend Manifesto they were angered. This hurt President Pierce's chances at presidency. This also helped splinter the Democratic Party.
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The Communist Manifesto was a product of the social, economic, and political turmoil that characterized Europe before 1850. This historical circumstance led to the publication of the manifesto by Marx and Engels.
Many, but perhaps Karl Marx was most notable for that in his book, "The Communist Manifesto".
The Communist Manifesto remains controversial in political and economic discussions. It received praise for its insight into labor and production and championing proletariat rights, and is criticized for encouraging too much government control over economics.
the significance is that France Great Britain and Russia where in an alliance
I would suggest the following: The Ninety-Five Theses The Magna Carta The Universal Declaration of Human Rights The Communist Manifesto The Treaty of Versailles The Treaty of Maastericht