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Maine would have to join as a free state so Missouri could become a slave state.
It is the 36030'N line that diveded the free states and the slave states in the 1820's when the Missouri Compromise was formed. Actually it was in 1850's ~Hope I could help
The Missouri Compromise of 1820 was important because it played a significant role in the relationship between the North and the South. It resulted in the admission of Missouri to the Union as a slave state.
Answer this question… Slavery would be permanently allowed in the South.
It was only unconstitutional if you accepted Roger Taney's interpretation of the Constitution in his judgment of the Dred Scott case in 1857. He said the Constitution protected slavery - so therefore no state could declare itself to be free soil.