The distance between Rome and Tunis (which is where Carthage was) as the crow flies is 600 kilometres (373 miles). If you sail around Sicily, as it is often done, to go there the sailing distance would be longer. Tunisia is close to Sicily, which was a Roman territory. The ferry ride from Trapani in western Sicily to Tunis is 218 km (136 miles).
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Rome to Pescara is about a 2.5 hour drive. The distance is 96 miles or about 154km.
Far from being the enemy of Rome, Alaric worked as king-maker, installing Priscus Attalus as emperor, and keeping him there despite policy disagreements. It didn't work. Ultimately, Rome's refusals to accommodate a barbarian led Alaric to sack Rome on August 24, A.D. 410.
Emperor Constantine the Great moved the capital of the Byzantine/Roman Empire from Rome to Constantinople around 330 AD. He felt that Rome was an unsatisfactory capital. Rome was too far from the frontiers. Constantinople provided easy trade and military access to the Mediterranean, Black Sea, Danube River, Dnieper River, and the land route to Turkestan and India.
No, 20,000 years ago is way too far back for the Romans. The city of Rome was founded in 753 BC. However before this actual founding, the forerunners of the people who would be known as Romans were living there in clusters of small villages. They united to form Rome.
Agriculture was by far the biggest economic sector in the ancient Roman economy (as with all pre-industrial societies). Trade was the engine of economic prosperity.