Not directly.
The main reasons were commercial - the import taxes which fell most heavily on the South, and the fate of the cotton revenues in the event of secession.
The human rights factor was secondary, although the Abolitionist lobby had become increasingly powerful in Congress.
Lincoln had been nominated and elected because he was moderate on slavery. When he rejected the final attempt at Compromise, it was not because he was insisting on abolition. He was only refusing to allow any new slave-states. The South could see their voting power in Congress slipping away, and that is why they became more belligereent.
You could say that the extension of slavery was a major trigger for the start of hostilities.
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Although it was a major cause, it was not the most important. The South had thought that, because Lincoln was in office and he was against slavery, that they were going to lose their way of life, and the only thing to do was secede from the country. Thus, the Civil War.
The main cause of the civil war was a battle over states rights.
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The most significant cause in the Civil War was unfair taxation, states' rights and slavery.
There are several questions about the civil war. The main questions which historians have about the war however, is if it was inevitable.
the main reason was the slavery rights