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The Missouri Compromise made slavery illegal in much of the US, except for the state of Missouri. Some people believe that this made the Civil War erupt later than it would have without the compromise.
People complained about having slaves. Some people liked having slaves and some people didn't. In the end, Missouri was a slave state and Maine was a free state.
It would allow slavery to spread north of the line established by the Missouri compromise. - Novanet
The Missouri Compromise was used to please both pro and anti-slavery people from the North and South with a regulation that prohibited slavery in some states and allowed it in other.
No. It replaced it with a deal - California to be admitted as a free state, with certain concessions to appease the South, including tightening-up the Fugitive Slave Act. It was the last-minute Crittenden Compromise that was meant to restore the Missouri Line, but Lincoln rejected this compromise, because it would have allowed some extension of slavery.