Many European settlements did occur between the years 1500 and 1770. However, most of the European migration and settlement happened between the 1640s and 1770, as English began to settle the islands in the New World.
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Yes, the Europeans did BRING the bible to the Americas, along with the majority of our culture.
Had no natural protection from diseases brought by Europeans.
Africa
Small pox. The natives had no resistence to diseases the europeans carried to the new world.