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Not much. He proved that the world was larger than first thought, that other people existed, but for the most part he was a failure. He didn't find gold nor a water route to India. His son had to sue the crown after his death because they refused to honor the terms of the contract they made with him.
because they had the columbian exchange; columbian exchange is a global exchange of goods and ideas
the Columbian exchange
the introduction of smallpox
Fur and other goods.
Europe