The most serious disagreement in the debate between large and small states at the Constitutional Convention was the issue of representation. Small states feared that their voices would be lost if representatives were chosen based on population, while big states didn't think it was fair that the small states would have as much influence as they had.
Slavery!
The biggest point of disagreement between the Northern and Southern states after the Civil War was secession. The Southern states did not accept the fact that secession goes against the constitution.
If you mean in the past, it would be whether or not the owning of states was a good or bad thing. South wanted slaves, North did not. The Civil War was a result of this disagreement.
The existence and growth of sectional and class differences in the United States were in fact revealed and also 'foreshadowed' in various ways by events after the (American rather than French) Revolutionary War in the 1780s. The 1787 Constitutional Convention, for instance, highlighted yet again the increasing difference between Southern mindsets and Northern, with 'class' distinctions showing up as significant between convention-delegates as well as within the home-regions of those same delegates.
Southern
There was a major disagreement between the states over representation in Congress.
The northern and southern states had two major disagreements at the convention. The North disagreed with the use of slaves, and the South disagreed how people were elected to office.
D. whether the federal government should have the power to regulate slavery.
counting slaves in the population
The Disagreement
Slavery!
Georgia
The biggest point of disagreement between the Northern and Southern states after the Civil War was secession. The Southern states did not accept the fact that secession goes against the constitution.
Because they their internet
im not sure
Blacks should be given the right to vote.
Virginia was a Southern Colony, and became and will forever be a member of the Southern States of the USA.