Diseases, in the form of foreign bacteria.
some examples are: smallpox (especially infectious and deadly to those unexposed to it before) and influensa (flu)
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The most devastating thing that Europeans brought to the Americas was diseases that natives were not immune to.
Tobacco
Christopher Columbus killed many many Native Americans. Europeans also killed many by bringing diseases to america. They (the British and europeans) were sick people, and very greedy, which is why there are very little Native Americans left.
the answer is the war pooped on America
a long-running pattern of whites removing Native Americans from their land, their lifestyle, and killing them.
run Native Americans off their land, destroy their culture, and kill them.